CAPN9 Antibody

Catalog Number:

46401

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O14815
NCBI Gene ID:10753
NCBI Protein:NP_006606

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human CAPN9

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CAPN9 protein.

Applications:

IHC

Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF