CAPN3 Antibody

Catalog Number:

46400

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P20807
NCBI Gene ID:825
NCBI Protein:BC003521

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human CAPN3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CAPN3 protein.

Applications:

IHC

Background:

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF