CAMK2A Antibody

Catalog Number:

46394

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UQM7
NCBI Gene ID:815
NCBI Protein:NP_741960

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CAMK2A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CAMK2A protein.

Applications:

IHC

Background:

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.?

References:

appl_detail:

Immunohistochemistry: 1: 40-200

Datasheet PDF