CALML6 Antibody

Catalog Number:

46393

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8TD86
NCBI Gene ID:163688
NCBI Protein:NP_619650

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human CALML6

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CALML6 protein.

Applications:

IHC

Background:

The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), a universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases and is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turnover and smooth muscle contraction. CALML6 (calmodulin-like 6), also known as CAGLP or CALGP, is a 181 amino acid protein that contains four EF-hand domains and shares functional similarity with CaM. Localized to both the nucleus and the cytoplasm, CALML6 is expressed in heart, prostate, ovary, thymus and bone marrow where it may regulate calcium-related events.

References:

appl_detail:

Immunohistochemistry: 1: 40-200

Datasheet PDF