CACNA1H Antibody

Catalog Number:

46383

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O95180
NCBI Gene ID:8912
NCBI Protein:NP_066921

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CACNA1H

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CACNA1H protein.

Applications:

IHC

Background:

This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).?

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF