CA11 Antibody

Catalog Number:

46377

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O75493
NCBI Gene ID:770
NCBI Protein:BC002662

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human CA11

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CA11 protein.

Applications:

IHC

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.?

References:

appl_detail:

Immunohistochemistry: 1: 40-200

Datasheet PDF