C21orf2 Antibody

Catalog Number:

46369

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O43822
NCBI Gene ID:755
NCBI Protein:BC031300

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human C21orf2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total C21orf2 protein.

Applications:

IHC

Background:

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.?

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF