BPGM Antibody

Catalog Number:

46351

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P07738
NCBI Gene ID:669
NCBI Protein:BC017050

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human BPGM

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BPGM protein.

Applications:

WB IHC

Background:

2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 50-300

Datasheet PDF