BHMT2 Antibody

Catalog Number:

46347

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9H2M3
NCBI Gene ID:23743
NCBI Protein:BC020665

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human BHMT2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BHMT2 protein.

Applications:

WB IHC

Background:

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150

Datasheet PDF