BCHE Antibody

Catalog Number:

46340

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P06276
NCBI Gene ID:590
NCBI Protein:BC008396

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human BCHE

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BCHE protein.

Applications:

IHC

Background:

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

References:

appl_detail:

Immunohistochemistry: 1: 50-300

Datasheet PDF