BAIAP2L1 Antibody

Catalog Number:

46330

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UHR4
NCBI Gene ID:55971
NCBI Protein:BC013888

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human BAIAP2L1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BAIAP2L1 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 30-150

Datasheet PDF