AVPR1B Antibody

Catalog Number:

46325

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P47901
NCBI Gene ID:553
NCBI Protein:NP_000698

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human AVPR1B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total AVPR1B protein.

Applications:

IHC

Background:

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

References:

appl_detail:

Immunohistochemistry: 1: 10-50

Datasheet PDF