CEP170 Antibody

Catalog Number:

46474

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5SW79
NCBI Gene ID:9859
NCBI Protein:NP_055627

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CEP170

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEP170 protein.

Applications:

WB IHC

Background:

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 10-50

Datasheet PDF