BSPRY Antibody

Catalog Number:

43996

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5W0U4
NCBI Gene ID: 54836

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human BSPRY

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BSPRY protein.

Applications:

IHC

Background:

BSPRY (B-box and SPRY domain containing) is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF