WNT5A Antibody

Catalog Number:

43980

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P41221
NCBI Gene ID: 7474

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WNT5A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WNT5A protein.

Applications:

IHC

Background:

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 10-50

Datasheet PDF