WDSUB1 Antibody

Catalog Number:

43977

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N9V3
NCBI Gene ID: 151525

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WDSUB1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WDSUB1 protein.

Applications:

IHC WB

Background:

WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1,400 genes and comprises nearly 8% of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr?m syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

Datasheet PDF