MTHFR Antibody

Catalog Number:

43966

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P42898
NCBI Gene ID: 4524

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human MTHFR

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MTHFR protein.

Applications:

IHC

Background:

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF