NF1 Antibody

Catalog Number:

43965

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P21359
NCBI Gene ID: 4763

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human NF1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NF1 protein.

Applications:

IHC WB

Background:

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

Datasheet PDF