RPTOR Antibody

Catalog Number:

43933

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N122
NCBI Gene ID: 57521

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human RPTOR

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total RPTOR protein.

Applications:

IHC

Background:

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF