KCNH1 Antibody

Catalog Number:

43927

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95259
NCBI Gene ID: 3756

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human KCNH1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KCNH1 protein.

Applications:

IHC

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF