KLRC3 Antibody

Catalog Number:

43916

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q07444
NCBI Gene ID: 3823

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human KLRC3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLRC3 protein.

Applications:

IHC

Background:

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF