TRIM23 Antibody

Catalog Number:

43914

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P36406
NCBI Gene ID: 373

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human TRIM23

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRIM23 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF