WDFY2 Antibody

Catalog Number:

43896

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96P53
NCBI Gene ID: 115825

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human WDFY2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WDFY2 protein.

Applications:

IHC WB

Background:

WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 30-150

Datasheet PDF