C16orf45 Antibody

Catalog Number:

43870

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96MC5
NCBI Gene ID: 89927

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human C16orf45

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total C16orf45 protein.

Applications:

IHC

Background:

C16orf45, also known as FLJ32618, is a 204 amino acid protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF