EMC7 Antibody

Catalog Number:

43869

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPA0
NCBI Gene ID: 56851

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human EMC7

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EMC7 protein.

Applications:

IHC

Background:

EMC7, also known as C15orf24, which encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The C15orf24 gene product has been provisionally designated C15orf24 pending further characterization.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF