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C14orf2 Antibody

Catalog Number:

43868
other_names: MP68; PLPM

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P56378
NCBI Gene ID: 9556

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human C14orf2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total C14orf2 protein.

Applications:

IHC

Background:

C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

References:

appl_detail:


Immunohistochemistry: 1: 30-150

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