ANAPC15 Antibody

Catalog Number:

43865

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P60006
NCBI Gene ID: 25906

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ANAPC15

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ANAPC15 protein.

Applications:

IHC

Background:

ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF