CYP11B2 Antibody

Catalog Number:

43862

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19099
NCBI Gene ID: 1585

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CYP11B2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYP11B2 protein.

Applications:

IHC

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

References:

appl_detail:

Immunohistochemistry: 1: 100-300

Datasheet PDF