ENPP2 Antibody

Catalog Number:

43857

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13822
NCBI Gene ID: 5168

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ENPP2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ENPP2 protein.

Applications:

IHC

Background:

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF