UBE4B Antibody

Catalog Number:

43828

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95155
NCBI Gene ID: 10277

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human UBE4B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBE4B protein.

Applications:

IHC

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF