WHSC1 Antibody

Catalog Number:

43810

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O96028
NCBI Gene ID: 7468

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WHSC1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WHSC1 protein.

Applications:

IHC

Background:

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF