XRN1 Antibody

Catalog Number:

43803

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IZH2
NCBI Gene ID: 54464

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human XRN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total XRN1 protein.

Applications:

IHC WB

Background:

This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 10-50

Datasheet PDF