CDK14 Antibody

Catalog Number:

43794

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O94921
NCBI Gene ID: 5218

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CDK14

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDK14 protein.

Applications:

WB

Background:

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

References:

appl_detail:

Western blotting: 1:200-1000

Datasheet PDF