MAGEB5 Antibody

Catalog Number:

43750

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BZ81
NCBI Gene ID: 347541

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human MAGEB5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAGEB5 protein.

Applications:

IHC

Background:

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B5 (melanoma-associated antigen B5), also known as CT3.3 (cancer/testis antigen 3.3), is a 275 amino acid protein that contains one MAGE domain and is expressed in testis. The gene encoding MAGE-B5 maps to human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently, as males carry a single X chromosome.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF