LRRC23 Antibody

Catalog Number:

43748

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q53EV4
NCBI Gene ID: 10233

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human LRRC23

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total LRRC23 protein.

Applications:

IHC

Background:

The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic ?/¡Ò horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF