IGF1R Antibody

Catalog Number:

43735

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P08069
NCBI Gene ID: 3480

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human IGF1R

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total IGF1R protein.

Applications:

IHC

Background:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF