HOXD10 Antibody

Catalog Number:

43732

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28358
NCBI Gene ID: 3236

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HOXD10

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HOXD10 protein.

Applications:

IHC WB

Background:

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

Datasheet PDF