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GKN1 Antibody

Catalog Number:

43725
other_names: FOV; CA11; AMP18; BRICD1; foveolin

Amount:

100μg
calculated_mw: 22kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NS71
NCBI Gene ID: 56287

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human GKN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total GKN1 protein.

Applications:

IHC WB

Background:

Gastrokine 1 (GKN1), a stomach-speci?c protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

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