DLK2 Antibody

Catalog Number:

43718

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6UY11
NCBI Gene ID: 65989

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DLK2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DLK2 protein.

Applications:

IHC

Background:

DLK2 (delta homolog 2), also known as EGFL9 (Epidermal growth factor-like protein 9), is a 383 amino acid single-pass transmembrane protein with six tandem EGF-like repeats in the putative extracellular domain, which is characteristic of the EGF-like protein family. DLK2 shares nearly identical structural features with DLK, suggesting that it may function in a similar way. Like DLK, DLK2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells, yet it does so in an opposite way to that of DLK. Also, expression of DLK and DLK2 are inversely correlated and changes in expression of one gene will affect the expression levels of the other. Therefore, it is likely that adipogenesis is modulated by the coordinated expression of DLK and DLK2. There are two isoforms of DLK2 that are produced as a result of alternative splicing events.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF