PTPRG Antibody

Catalog Number:

43700

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P23470
NCBI Gene ID: 5793

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human PTPRG

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTPRG protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF