BRI3BP Antibody

Catalog Number:

43694

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WY22
NCBI Gene ID: 140707

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human BRI3BP

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BRI3BP protein.

Applications:

IHC WB

Background:

BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

References:

appl_detail:

Western blotting: 1:500-2000
Immunohistochemistry: 1: 30-150

Datasheet PDF