HDAC4 Antibody

Catalog Number:

43687

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P56524
NCBI Gene ID: 9759

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HDAC4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HDAC4 protein.

Applications:

IHC

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF