E2F3 Antibody

Catalog Number:

43667

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00716
NCBI Gene ID: 1871

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human E2F3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total E2F3 protein.

Applications:

IHC

Background:

This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF