KMT2B Antibody

Catalog Number:

43660

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UMN6
NCBI Gene ID: 9757

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human KMT2B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KMT2B protein.

Applications:

IHC

Background:

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.?

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF