SULF2 Antibody

Catalog Number:

43638

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IWU5
NCBI Gene ID: 55959

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SULF2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SULF2 protein.

Applications:

IHC

Background:

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF