SIN3B Antibody

Catalog Number:

43634

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O75182
NCBI Gene ID: 23309

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SIN3B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SIN3B protein.

Applications:

IHC

Background:

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF