UMPS Antibody

Catalog Number:

43615

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P11172
NCBI Gene ID: 7372

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human UMPS

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UMPS protein.

Applications:

IHC WB

Background:

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.?

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 30-150

Datasheet PDF