UBA7 Antibody

Catalog Number:

43610

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P41226
NCBI Gene ID: 7318

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human UBA7

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBA7 protein.

Applications:

IHC

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF