VPREB3 Antibody

Catalog Number:

43594

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UKI3
NCBI Gene ID: 29802

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human VPREB3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VPREB3 protein.

Applications:

IHC

Background:

The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF