ZNF346 Antibody

Catalog Number:

43579

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UL40
NCBI Gene ID: 23567

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ZNF346 protein.

Applications:

IHC WB

Background:

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 30-150

Datasheet PDF